ATP synthase



ATP synthase (ATPS) also known as V-ATPase, catalyzes the synthesis of ATP from ADP and phosphate. In mitochondria, the F1F0 ATPS contains the F0 membranal part (F1-ATPS). Its subunits are named by Greek or Roman letters. The images at the left and at the right correspond to one representative ATPS, i.e. the crystal structure of yeast yATPS, subunit H (1ho8).

3D Structures of ATP synthase
Update June 2011

V-ATPase
1ho8 – yATPS subunit H – yeast

1u7l - yATPS subunit C

2k88 - yATPS subunit G - NMR

2bl2, 2cyd - ATPS subunit K – Enterococcus hirae

2c61 - MmATPS subunit B – Methanosarcina mazei

2rkw, 3b2q, 3eiu - MmATPS subunit B (mutant)

3dsr - MmATPS subunit B+ADP

2ov6 - MmATPS subunit F - NMR

1r5z, 1v9m - TtATPS subunit C – Thermus thermophilus

2d00 - TtATPS subunit F

3a5c, 3a5d - TtATPS subunit A,B,D,F

3gqb - TtATPS subunit A,B

3k5b - TtATPS subunit E (mutant)+C

2dm9, 2dma - PhATPS subunit E – Pyrococcus horikoshii

3i4l - PhATPS subunit A+AMPPNP

3mfy, 3m4y, 3nd8, 3nd9, 3p20 - PhATPS subunit A (mutant)

3i72, 3i73, 3ikj - TtATPS subunit A (mutant)

2qai - ATPS subunit F – Pyrococcus furiosus

2i4r - ATPS subunit F – Archaeoglobus fulgidus

2kk7 - MjATPS subunit E – Methanocaldococcus jannaschii

3lg8 - MtATPS subunit C C-terminal

2w5j - ATPS subunit C - spinach

F1F0 ATPase
1ohh – α,β,γ bF1-ATPS+ IF1 inhibitor – bovine

1e1q, 2w6e, 2w6f, 2w6g, 2w6h, 2w6i, 2w6j - α,β,γ bF1-ATPS

1e1r - α,β,γ bF1-ATPS+Mg+ADP+AlF4

1w0j, 1w0k - α,β,γ bF1-ATPS+BeF3

1bmf - bF1-ATPS

3dze – bF1-ATPS subunit S

1cow - bF1-ATPS+aurovertin B

1nbm - α,β,γ bF1-ATPS+nitrobenzofurazan

2v7q - α,β,γ,δ,ε bF1-ATPS+inhibitor

2xnd, 2xok - α,β,γ,δ,ε bF1-ATPS+ATPS lipid-binding protein

2jmx - α bF1-ATPS+subunit O

1a91, 1c0v – EcF1-ATPS subunit C - Escherichia coli – NMR

2a7u – α N-terminal, δ N-terminal EcF1-ATPS – NMR

2khk - EcF1-ATPS subunit B fragment – NMR

3oaa – a,b,g,e EcF1-ATPS (mutant)

1mab - α,β,γ F1-ATPS – rat

1sky – α3,β3 BsF1-ATPS – Bacillus sp. Ps3

1wu0 - BsATPS subunit C – NMR

2r9v - α F1-ATPS – Thermotoga maritima

2rq6, 2rq7 - ε F1-ATPS – Thermosynechococcus elongates

2wgm – F0-ATPS subunit C – Ilyobacter tartaricus

2wpd, 2wss - α,β,γ,δ,ε yF1-ATPS+subunit 9+Mg+ADP+ATP

2x2v – F0-ATPS subunit C – Bacillus pseudofirmus

3oe7, 3oee, 3oeh, 3ofn - α,β,γ,δ,ε yF1-ATPS (mutant)

3fks - a,b,g,d,e yF1-ATPS